Kinetics and mechanism of the anilinolysis of aryl phenyl isothiocyanophosphates in acetonitrile

• Hasi Rani Barai and
• Hai Whang Lee

Beilstein J. Org. Chem. 2013, 9, 615–620, doi:10.3762/bjoc.9.68

• . Keywords: anilinolysis; cross-interaction constant; deuterium kinetic isotope effects; phosphoryl transfer reaction; reactive intermediates; Y-aryl phenyl isothiocyanophosphates; Introduction The nucleophilic substitution reactions of tetracoordinate phosphorus have been studied extensively

• increases with a more electron-withdrawing substituent. The cross-interaction constant (CIC) is defined based on the substituent effects of the nucleophiles, substrates and/or leaving groups on the reaction rates [3][4][5]. In the present work, the CIC (ρXY) between substituents X and Y in the nucleophiles